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Publications

Bruxelles Woluwe

  1. Identification and in vivo detection of side-chain hydroxylated metabolites of 4β-hydroxycholesterol.
    Roumain M, Guillemot-Legris O, Ameraoui H, Alhouayek M, Muccioli GG. 
    J Steroid Biochem Mol Biol. 2023;234:106376. doi: 10.1016/j.jsbmb.2023.106376
  2. Set up and validation of a sensitive method to quantify prostaglandins, prostaglandin-glycerol esters and prostaglandin-ethanolamides, as well as their respective precursors.
    Paquot A, Bestard-Escalas J, Muccioli GG.
    Prostaglandins Other Lipid Mediat. 2023;168:106763. doi:10.1016/j.prostaglandins.2023.106763
  3. Genetic Polymorphisms in SLCO2B1 and ABCC1 conjointly modulate atorvastatin intracellular accumulation in HEK293 recombinant cell lines.
    Hoste E, Paquot A, Panin N, Horion S, El Hamdaoui H, Muccioli GG, Haufroid V, Elens L.
    Ther Drug Monit. 2023;45(3):400-408. doi: 10.1097/FTD.0000000000001043.
  4. Lipid nanocapsules for the nose-to-brain delivery of the anti-inflammatory bioactive lipid PGD2-G.
    Mwema A, Bottemanne P, Paquot A, Ucakar B, Vanvarenberg K, Alhouayek M, Muccioli GG, des Rieux A.
    Nanomedicine. 2023 Feb;48:102633. doi: 10.1016/j.nano.2022.102633.
  5. Quality-by-design-based development of a voxelotor self-nanoemulsifying drug-delivery system with improved biopharmaceutical attributes.
    Buya AB, Terrasi R, Mbinze JK, Muccioli GG, Beloqui A, Memvanga PB, Préat V.
    Pharmaceutics. 2021 Sep 2;13(9):1388. doi: 10.3390/pharmaceutics13091388.
  6. Novel insights into the genetically obese (ob/ob) and diabetic (db/db) mice: two sides of the same coin.
    Suriano F, Vieira-Silva S, Falony G, Roumain M, Paquot A, Pelicaen R, Régnier M, Delzenne NM, Raes J, Muccioli GG, Van Hul M, Cani PD. 
    Microbiome 2021;9(1):147. doi: 10.1186/s40168-021-01097-8.
  7. Inflammation-induced cholestasis in cancer cachexia.
    Thibaut MM, Sboarina M, Roumain M, Pötgens SA, Neyrinck AM, Destrée F, Gillard J, Leclercq IA, Dachy G, Demoulin JB, Tailleux A, Lestavel S, Rastelli M, Everard A, Cani PD, Porporato PE, Loumaye A, Thissen JP, Muccioli GG, Delzenne NM, Bindels LB.
    J Cachexia Sarcopenia Muscle . 2021;12(1):70-90. doi: 10.1002/jcsm.12652.
  8. Longitudinal study of Pex1-G844D NMRI mouse model: A robust pre-clinical model for mild Zellweger spectrum disorder.
    Demaret T, Roumain M, Ambroise J, Evraerts J, Ravau J, Bouzin C, Bearzatto B, Gala JL, Stepman H, Marie S, Vincent MF, Muccioli GG, Najimi M, Sokal EM.
    Biochim Biophys Acta Mol Basis Dis. 2020 Nov 1;1866(11):165900. doi: 10.1016/j.bbadis.2020.165900.
  9. Intestinal NAPE-PLD contributes to short-term regulation of food intake via gut-to-brain axis.
    Rastelli M, Van Hul M, Terrasi R, Lefort C, Régnier M, Beiroa D, Delzenne NM, Everard A, Nogueiras R, Luquet S, Muccioli GG, Cani PD.
    Am J Physiol Endocrinol Metab. 2020 Sep 1;319(3):E647-E657. doi: 10.1152/ajpendo.00146.2020
  10. Lysophosphatidylinositols in inflammation and macrophage activation: Altered levels and anti-inflammatory effects.
    Masquelier J, Alhouayek M, Terrasi R, Bottemanne P, Paquot A, Muccioli GG.
    Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Dec;1863(12):1458-1468. doi: 10.1016/j.bbalip.2018.09.003. PMID: 30251703
  11. Phenolic profiling in the pulp and peel of nine plantain cultivars (Musa sp.).
    Passo Tsamo CV, Herent MF, Tomekpe K, Happi Emaga T, Quetin-Leclercq J, Rogez H, Larondelle Y, Andre C.
    Food Chem. 2015 Jan 15;167:197-204.
  12. Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota.
    Geurts L, Everard A, Van Hul M, Essaghir A, Duparc T, Matamoros S, Plovier H, Castel J, Denis RG, Bergiers M, Druart C, Alhouayek M, Delzenne NM, Muccioli GG, Demoulin JB, Luquet S, Cani P.D.
    Nat. Commun., 6, 6495.
  13. Modulation of the activity of moxifloxacin and solithromycin in an in vitro pharmacodynamic model of Streptococcus pneumoniae naive and induced biofilms.
    Vandevelde NM, Tulkens PM, Muccioli GG, Van Bambeke F.
    J. Antimicrob. Chemother., 70(6), 1713-1726
  14. Intestinal epithelial MyD88 is a sensor switching host metabolism towards obesity according to nutritional status.
    Everard A, Geurts L, Caesar R, Van Hul M, Matamoros S, Duparc T, Denis RG, Cochez P, Pierard F, Castel J, Bindels LB, Plovier H, Robine S, Muccioli GG, Renauld JC, Dumoutier L, Delzenne NM, Luquet S, Bäckhed F, Cani P.D.
    Nat Commun., 5, 5648
  15. Synthesis, half-wave potentials and antiproliferative activity of 1-aryl-substituted aminoisoquinolinequinones. 
    Ibacache JA, Delgado V, Benites J, Theoduloz C, Arancibia V, Muccioli GG, Valderrama J.A.
    Molecules, 19(1), 726-739
  16. Chemical composition, cytotoxicity and in vitro antitrypanosomal and antiplasmodial activity of the essential oils of four Cymbopogon species from Benin.
    Kpoviessi S, Bero J, Agbani P, Gbaguidi F, Kpadonou-Kpoviessi B, Sinsin B, Accrombessi G, Frédérich M, Moudachirou M, Quetin-Leclercq J.
    J. Ethnopharmacol., 151(1), 652-659
  17. Effect of Drug-Targeting Nebulization on Lung Delivery.
    Reychler G, Aubriot AS, Masquelier J, Muccioli GG, Liistro G
    Arch Bronconeumol. 2013 Dec 28. pii: S0300-2896(13)00356-6
  18. Implication of the anti-inflammatory bioactive lipid prostaglandin D2-glycerol ester in the control of macrophage activation and inflammation by ABHD6.
    Alhouayek M, Masquelier J, Cani PD, Lambert DM, Muccioli GG
    Proc Natl Acad Sci U S A. 2013; 110(43):17558-63.
  19. Eco-friendly synthesis and antiproliferative evaluation of some oxygen substituted diaryl ketones.
    Arenas P, Peña A, Ríos D, Benites J, Muccioli GG, Calderon PB, Valderrama JA
    Molecules. 2013;18(8):9818-32
  20. Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity.
    Everard A, Belzer C, Geurts L, Ouwerkerk JP, Druart C, Bindels LB, Guiot Y, Derrien M, Muccioli GG, Delzenne NM, de Vos WM, Cani PD.
    Proc Natl Acad Sci U S A. 2013 May 13.
  21. Fast method for the simultaneous quantification of toxic polyphenols applied to the selection of genotypes of yam bean (Pachyrhizus sp.) seeds.
    Lautié E, Rozet E, Hubert P, Vandelaer N, Billard F, Zum Felde T, Grüneberg WJ, Quetin-Leclercq J.
    Talanta. 2013 Dec 15;117:94-101.
  22. Mass spectrometric characterization of organosulfates related to secondary organic aerosol from isoprene.
    Safi Shalamzari M, Ryabtsova O, Kahnt A, Vermeylen R, Hérent MF, Quetin-Leclercq J, Van der Veken P, Maenhaut W, Claeys M.
    Rapid Commun Mass Spectrom. 2013 Apr 15;27(7):784-94.
  23. Piceatannol, a potent bioactive stilbene, as major phenolic component in Rhodomyrtus tomentosa.
    Lai TN, Herent MF, Quetin-Leclercq J, Nguyen TB, Rogez H, Larondelle Y, André CM.
    Food Chem. 2013 Jun 1;138(2-3):1421-30
  24. In vivo antimalarial activity of Keetia leucantha twigs extracts and in vitro antiplasmodial effect of their constituents.
    Bero J, Hérent MF, Schmeda-Hirschmann G, Frédérich M, Quetin-Leclercq J.
    J Ethnopharmacol. 2013 Aug 26;149(1):176-83. doi:
  25. Fast microwave-assisted extraction of rotenone for its quantification in seeds of yam bean (Pachyrhizus sp.).
    Lautié E, Rasse C, Rozet E, Mourgues C, Vanhelleputte JP, Quetin-Leclercq J.
    J Sep Sci. 2013 Feb;36(4):758-63.
  26. Antitrypanosomal compounds from the essential oil and extracts of Keetia leucantha leaves with inhibitor activity on Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase.
    Bero J, Beaufay C, Hannaert V, Hérent MF, Michels PA, Quetin-Leclercq
    J. Phytomedicine. 2013 Feb 15;20(3-4):270-4.
  27. Development and validation of an UHPLC-LTQ-Orbitrap MS method for non-anthocyanin flavonoids quantification in Euterpe oleracea juice.
    Dias AL, Rozet E, Larondelle Y, Hubert P, Rogez H, Quetin-Leclercq J.
    Anal Bioanal Chem. 2013 Nov;405(28):9235-49
  28. Degradation of rotenone in yam bean seeds ( Pachyrhizus sp.) through food processing. 
    Catteau L, Lautié E, Koné O, Coppée M, Hell K, Pomalegni CB, Quetin-Leclercq J.
    J Agric Food Chem. 2013 Nov 20;61(46):11173-9
  29. Chronic endocannabinoid system stimulation induces muscle macrophage and lipid accumulation in type 2 diabetic mice independently of metabolic endotoxaemia.
    Geurts L, Muccioli GG, Delzenne NM, Cani PD.
    PLoS One. 2013;8(2):e55963.
  30. The association of N-palmitoylethanolamine with the FAAH inhibitor URB597 impairs melanoma growth through a supra-additive action.
    Hamtiaux L , Masquelier J, Muccioli GG , C. Bouzin C, Feron O, Gallez B, Lambert D.M .
    BMC Cancer, 2012, 12(92): 1-14
  31. Differential modulations of striatal tyrosine hydroxylase and dopamine metabolism by cannabinoid agonists as evidence for functional selectivity in vivo.
    Bosier B, Muccioli GG, Mertens B, Sarre S, Michotte Y, Lambert DM, Hermans E. Neuropharmacology, 2012, 62: 2327- 2335
  32. Gut microbiota-derived propionate reduces cancer cell proliferation in the liver.
    Bindels LB, Porporato P, Dewulf EM, Verrax J, Neyrinck AM, Martin JC, Scott KP, Buc Calderon P, Feron O, Muccioli GG, Sonveaux P, Cani P.D., Delzenne N.M.
    British Journal of Cancer, 2012: 1–8
  33. Synthesis and pharmacological evaluation of 2,4-dinitroaryldithiocarbamate derivatives as novel monoacylglycerol lipase inhibitors.
    C. N. Kapanda, J. Masquelier, G. Labar, G. G. Muccioli, J. H. Poupaert, D. M. Lambert
    Journal of Medicinal Chemistry, 2012, 55, 5774−5783
  34. Funcionalized phosphonated half-cage molecules as ligands for metal complexes.
    E. Villemin, M.-F. Hérent, J. Marchand-Brynaert.
    European Journal of Organic Chemistry, 31, 6165-6178, 2012
  35. Anti-inflammatory effects of pomegranate (Punica granatum L.) husk ellagitannins in Caco-2 cells, an in vitro model of human intestine.
    S. Hollebeeck, J. Winand, M.-F. Herent, A. During, J. Leclercq, Y. Larondelle, Y.-J. Schneider.
    Food & Function, 3(8), 875-885, 2012.
  36. Antiparasitic activities of two sesquiterpenic lactones isolated from Acanthospermum hispidum. 
    D.C.Ganfon H. , Bero J., Tchinda A.T., Gbaguidi F., Gbenou J., Moudachirou M., Frédérich M., Quetin-Leclercq J.
    J. Ethnopharmacol., 141 (2012) : 411– 417
  37. Quantification of rotenone in seeds of different species of yam bean (Pachyrhizus sp.) by a SPE HPLC–UV method.
    Lautié E., Rozet E., Hubert P., Quetin Leclercq J.
    Food Chemistry 131(4) (2012): 1531-1538
  38. Characterization of an endophytic whorl-forming Streptomyces from Catharanthus roseus stems producing polyene macrolide antibiotic.
    Rakotoniriana E.F., Chataigné, G., Raoelison G., Rabemanantsoa C., Munaut F., El Jaziri M., Urveg-Ratsimamanga S., Marchand-Brynaert J., Corbisier A.-M., Declerck S., Quetin-Leclercq J.
    Can. J. Microbiol. 58 (2012) 617-627
  39. A rapid validated UHPLC–PDA method for anthocyanins quantification from Euterpe oleracea fruits.
    Dias A.L.S., Rozet E., Chataigné G., Oliveira A.C., Rabelo C.A.S., Hubert Ph., Rogez H., Quetin-Leclercq J.
    Journal of Chromatography B, 907 (2012) 108– 116
  40. SAR and LC/MS studies of β-lactamic inhibitors of human Fatty Acid Amide Hydrolase (hFAAH): Evidence of a Nonhydrolytic Process. 
    M. Feledziak, G. G. Muccioli, D. M. Lambert, J. Marchand-Brynaert
    Journal of Medicinal Chemistry, 2011, 54: 6812–6823
  41. Dual inhibition of α/β-hydrolase domain 6 and Fatty Acid Amide Hydrolase Increases endocannabinoid levels in neurons.
    W.R. Marrs, E. A. Horne, S. Ortega-Gutierrez, J. A.Cisneros, C. Xu, Y. Hsing Lin, G. G. Muccioli, M. L. Lopez-Rodriguez, N.Stella Journal of Biological Chemistry, 2011, 286(33): 28723-28728
  42. Altered gut microbiota and endocannabinoid system tone in obese and diabetic leptin-resistant mice: impact on apelin regulation in adipose tissue.
    L. Geurts, V. Lazarevic, M. Derrien, A. Everard, M. Van Roye, C. Knauf, P. Valet, M. Girard, G.G. Muccioli, P. François, W. M. deVos, J. Schrenzel, N.M. Delzenne, P.D. Cani.
    Frontiers in Microbiology, 2011, 2(149): 1-17
  43. Increasing endogenous 2-arachidonoylglycerol levels counteracts colitis and related systemic inflammation.
    M. Alhouayek, D. M. Lambert, N. M. Delzenne, P. D. Cani, G. G. Muccioli.
    The FASEB Journal, 2011, 25: 2711-2721
  44. Hepatic n-3 polyunsaturated fatty acid depletion promotes steatosis and insulin resistance in mice: genomic analysis of cellular targets.
    B. D. Pachikian, A. Essaghir, J.-B. Demoulin, A. M. Neyrinck, E. Catry, F. C. De Backer, N. Dejeans, E. M. Dewul1, F. M. Sohet, L. Portois, L. Deldicque, O. Molendi-Coste, I. A. Leclercq, M. Francaux, Y.A. Carpentier, F. Foufelle, G. G. Muccioli, P. D. Cani, N. M. Delzenne.
    PlosOne, 2011, 6(8) e23365: 1-13
  45. Increasing antiproliferative properties of endocannabinoids in N1E-115 neuroblastoma cells through inhibition of their metabolism.
    L. Hamtiaux, L. Hansoulle, N. Dauguet, G. G. Muccioli, B. Gallez, D. M. Lambert.
    PlosOne, 2011, 6(10) e26823: 1-14
  46. Lipid transport function is the main target of oral oleoylethanolamide to reduce adiposity in high-fat-fed mice.
    C. Thabuis, F. Destaillats, D. M. Lambert, G. G. Muccioli , M. Maillot, T. Harach , D. Tissot-Favre , J.-C.Martin.
    Journal of Lipid Research Volume, 2011, 52: 1373-1382
  47. Novel phosphonated bicyclic frameworks from Diels–Alder reaction as chelating agents of di- and trivalent metal cations.
    E. Villemin , B. Elias , R. Robiette , K. Robeyns , M.-F. Herent , J.-L. Habib-Jiwan, J. Marchand-Brynaert
    Tetrahedron Letters, 52, 5140-5144, 2011
  48. In vitro antitrypanosomal and antileishmanial activity of plants used in Benin in traditional medicine and bio-guided fractionation of the most active extract.
    J. Bero, V. Hannaert, G. Chataigné, M.-F. Hérent, J. Quetin-Leclercq.
    Journal of Ethnopharmacology, 137, 998-1002, 2011.
  49. Identification by LC-ESI-MS of flavonoids responsible for the antioxidant properties of mallotus species from Vietnam.
    V N.T. Hong, C. Rivière, Q. T. Hong, G.Chataigné, N.N. Hoai, B. Dejaegher, C. Tistaert, T. N.T. Kim, K. P. Van, Y. Vander Heyden, M. C. Van and J.Quetin-Leclercq.
    Natural Products Communications 6(6) (2011): 813-818
  50. The serine hydrolase ABHD6 controls 2-AG the accumulation and efficacy at cannabinoid receptors.
    W. Marrs, J. Blankman, E. Horne, A. Thomazeau, Y.H. Lin, J. Coy, A. Bodor, G.G. Muccioli, S. Shu-Jung Hu, G. Woodruff, S. Fung, M. Lafourcade, J. Alexander, J. Long, W. Li, C. Xu, T.Möller, K. Mackie, O. Manzoni, B. Cravatt, N. Stella
    Nature Neuroscience, 2010,13(8):951-7
  51. Molecular identification of N-acetylaspartylglutamate synthase and beta-citrylglutamate synthase.
    Collard F., Stroobant V., Lamosa P., Kapanda C.N., Lambert D.M., Muccioli G.G., Poupaert J.H., Opperdoes F., Van Schaftingen E.
    Journal of Biological Chemistry, 2010, 285, 29826-29833.
  52. The endocannabinoid system links gut microbiota to adipogenesis.
    G.G. Muccioli, D. Naslain, F. Bäckhed, C. Reigstad, D.M Lambert, N.M. Delzenne, P.D. Cani.
    Molecular Systems Biology, 2010, 6(392): 1-15
  53. Photodegradation of flupentixol in aqueous solution under irradiation at 254 nm : Identification of the photoproducts generated. A. Maquille, S. Salembier, M.-F. Hérent, J.-L. Habib Jiwan, Journal of Photochemistry and Photobiology A : Chemistry, 214, 224-229, 2010.
  54. Mallotus species from Vietnamese moutainous areas: phytochemistry and pharmacological activities
    C. Rivière, V. Nguyen Thi Hong, Q. Tran Hong, G. Chataigné, N. Nguyen Hoai, B. Dejaegher, C. Tistaert, T. Nguyen Thi Kim, Y. Vander Heyden, M. Chau Van, J. Quetin-Leclercq.
    Phytochemistry Reviews (2010) 9: 217-25
  55. Polyphenols isolated from antiradical extracts of Mallotus metcalfianus
    Rivière C. , V. Nguyen V., L. Pieters L., B. Dejargher B., Y. Vander Heyden Y., M. Chau Van M., J. Quetin-Leclercq J.
    Phytochemistry, 70, 91-99
  56. Genetic Manipulation of Palmitoylethanolamide Production and Inactivation in Saccharomyces cerevisiae.
    Muccioli G.G., A. Sia A., P. Muchowski P., N. Stella N.
    PlosOne, 4(6) e5942: 1-10